Virologist Matthias Götte and his team have discovered how the oral antiviral drug called molnupiravir works against the SARS-CoV-2 virus. The drug is under consideration for emergency use in India to stem the rapid spread of COVID-19. (Photo: Faculty of Medicine & Dentistry)

U of A lab reveals how a much-needed oral antiviral drug confuses the replication machinery of SARS-CoV-2

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Molnupiravir under consideration for emergency use in India to slow explosive spread of COVID-19 infections.

A University of Alberta virology lab has uncovered how an oral antiviral drug works to attack the SARS-CoV-2 virus, in findings published May 10 in the Journal of Biological Chemistry.

The researchers demonstrated the underlying mechanism of action by which the antiviral drug molnupiravir changes the viral genome, a process known as excessive mutagenesis or “error catastrophe….”

https://www.ualberta.ca/folio/2021/05/u-of-a-lab-reveals-how-a-much-needed-oral-antiviral-drug-confuses-the-replication-machinery-of-sars-cov-2.html

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